ETT

The convenient activator for RNA synthesis.

CAS: 89797-68-2

Synonym: 5-(Ethylthio)-1H-tetrazole

Properties

Purity

≥99.0%

Molecular Formula

C3H6N4S

Molecular Weight

130.17 [gr/mol]

Appearance

White to off-white crystalline powder

Storage Conditions

Store in a cool and dry place

Applications

  • ETT is much more soluble than 1H-tetrazole – the first activator for DNA synthesis.

Studies

  • Large Scale Synthesis of Oligonucleotides via Phosphoramidite Nucleosides and a High-loaded Polystyrene Support
    P. Wright, D. Lloyd, W. Rapp, and A. Anrus Tetrahedron let.,  1993, 34, 21,  3373-3376.
  • Synthesis and Macrodomain Binding of Mono-ADP-Ribosylated Peptides
    H. A. V. Kistemaker, A. Pio Nardozza, H. S. Overkleeft, G. A. van der Marel, A. G. Ladurner, and D. V. Filippov
    Angew. Chem. Int. Ed. 2016, 55, 10634–10638.
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